Michaela Kuhn Selected Research

Atrial Natriuretic Factor (ANF)

2/2022	Correction to: Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice.
1/2020	Natriuretic Peptides Attenuate Retinal Pathological Neovascularization Via Cyclic Guanosine Monophosphate Signaling in Pericytes and Astrocytes.
1/2018	β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice.
3/2016	Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice.
1/2016	Endothelial Actions of ANP Enhance Myocardial Inflammatory Infiltration in the Early Phase After Acute Infarction.
9/2014	Atrial natriuretic peptide locally counteracts the deleterious effects of cardiomyocyte mineralocorticoid receptor activation.
4/2013	Stress-dependent dilated cardiomyopathy in mice with cardiomyocyte-restricted inactivation of cyclic GMP-dependent protein kinase I.
11/2011	A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide.
9/2010	Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.
6/2010	Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern.

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Michaela Kuhn Research Topics

Disease

12	Cardiomegaly (Heart Hypertrophy) 01/2021 - 11/2002
8	Hypertrophy 01/2021 - 11/2004
8	Hypertension (High Blood Pressure) 01/2017 - 11/2002
6	Heart Failure 10/2022 - 11/2004
4	Hypoxia (Hypoxemia) 11/2021 - 01/2016
3	Heart Diseases (Heart Disease) 01/2018 - 06/2005
3	Inflammation (Inflammations) 03/2016 - 04/2006
3	Fibrosis (Cirrhosis) 09/2014 - 11/2002
3	Hypovolemia 05/2009 - 06/2005
2	Pulmonary Hypertension 02/2022 - 03/2016
2	Cardiomyopathies (Cardiomyopathy) 11/2021 - 09/2014
2	Albuminuria 01/2021 - 01/2017
2	Ischemia 01/2020 - 01/2016
2	Insulin Resistance 01/2018 - 08/2010
2	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 09/2014 - 11/2002
2	Infections 10/2005 - 01/2005
1	Barth Syndrome 11/2021
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021
1	Chronic Renal Insufficiency 01/2021
1	Kidney Diseases (Kidney Disease) 01/2021
1	Hidden Hearing Loss 01/2020
1	Growth Disorders 01/2020
1	Noise-Induced Hearing Loss (Acoustic Trauma) 01/2020
1	Pathologic Neovascularization 01/2020
1	Presbycusis 01/2020
1	Hyperoxia 01/2020
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2020
1	Hearing Loss (Hearing Impairment) 01/2020
1	Glucose Intolerance 01/2018
1	Weight Gain 01/2018
1	Obesity 01/2018
1	Infarction (Infarctions) 01/2016
1	Ventricular Remodeling 09/2014
1	Congenital Abnormalities (Deformity) 12/2013
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 04/2013
1	Blister (Bulla) 04/2006

Drug/Important Bio-Agent (IBA)

20	Atrial Natriuretic Factor (ANF)IBA 02/2022 - 11/2002
9	atrial natriuretic factor receptor AIBA 01/2020 - 11/2002
7	Natriuretic PeptidesIBA 10/2022 - 11/2004
4	Proteins (Proteins, Gene)FDA Link 11/2021 - 01/2005
4	Guanosine Monophosphate (5' Guanylic Acid)IBA 11/2021 - 04/2014
4	Atrial Natriuretic Factor Receptors (Atrial Natriuretic Factor Receptor)IBA 01/2020 - 11/2002
4	Messenger RNA (mRNA)IBA 10/2005 - 11/2002
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 08/2010
3	Angiotensin IIIBA 03/2016 - 09/2010
3	Phosphotransferases (Kinase)IBA 01/2016 - 10/2005
3	CytokinesIBA 01/2016 - 10/2005
2	Desoxycorticosterone (Deoxycorticosterone)IBA 01/2021 - 01/2017
2	SaltsIBA 01/2021 - 01/2017
2	Desoxycorticosterone Acetate (DOCA)FDA Link 01/2021 - 01/2017
2	Acetates (Acetic Acid Esters)FDA Link 01/2021 - 01/2017
2	Cyclic GMP-Dependent Protein Kinase Type IIBA 01/2020 - 09/2014
2	Hormones (Hormone)IBA 01/2018 - 10/2003
2	Losartan (Cozaar)FDA LinkGeneric 03/2016 - 11/2002
2	AldosteroneIBA 09/2014 - 01/2006
2	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 04/2013 - 09/2010
2	Brain Natriuretic Peptide (Natrecor)FDA Link 11/2010 - 11/2002
2	Guanylate Cyclase-Coupled ReceptorsIBA 05/2004 - 05/2003
1	MyokinesIBA 10/2022
1	RNA (Ribonucleic Acid)IBA 10/2022
1	Cardiolipins (Cardiolipin)IBA 11/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2021
1	Adenosine Triphosphatases (ATPase)IBA 11/2021
1	Adenosine Monophosphate (AMP)IBA 11/2021
1	CalpainIBA 01/2021
1	CalciumIBA 01/2021
1	Small Interfering RNA (siRNA)IBA 01/2021
1	Calcium Channels (Calcium Channel)IBA 01/2021
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2021
1	Drinking WaterIBA 01/2021
1	ConnectinIBA 11/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020
1	atrial natriuretic factor receptor BIBA 01/2020
1	Oxygen (Dioxygen)IBA 01/2020
1	Retinaldehyde (Retinal)IBA 01/2020
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2020
1	MicroRNAs (MicroRNA)IBA 01/2018
1	1- (2- (3- (4- methoxyphenyl)propoxy)- 4- methoxyphenylethyl)- 1H- imidazoleIBA 01/2017
1	MineralocorticoidsIBA 01/2017
1	AngiotensinsIBA 03/2016
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 03/2016
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2016
1	Type 2 Cyclic Nucleotide PhosphodiesterasesIBA 01/2016
1	Eplerenone (Inspra)FDA LinkGeneric 09/2014
1	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 09/2014
1	Guanylate Cyclase (Guanylyl Cyclase)IBA 09/2014
1	Cyclic GMPIBA 04/2013
1	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 04/2013
1	C-Type Natriuretic Peptide (Peptide, C-Type Natriuretic)IBA 04/2013
1	Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA 11/2010
1	Adrenergic Agents (Adrenergic Drugs)IBA 09/2010
1	GTP-Binding Proteins (G-Protein)IBA 09/2010
1	Interleukin-6 (Interleukin 6)IBA 04/2006
1	Free RadicalsIBA 04/2006
1	8-epi-prostaglandin F2alphaIBA 04/2006
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 10/2005
1	CalcineurinIBA 10/2005
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 10/2005
1	Mitogen-Activated Protein KinasesIBA 10/2005

Therapy/Procedure

1	Ligation 01/2020